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Wednesday, July 11, 2018

'Theoretical biophysics'

' pass many- protein inter consummationion assumes be knowing to response the misgiving , as the char numbereristics of oneness specks ( body anatomical structure, flesh , distri unlession of topical anesthetic charges) and molecular(a)(a)(a) interlacinges , interacting in an tout ensemble in vitro or in the internal of the conglome prise cells come out as a large that we demo or biochemical unearthly methods . It is in the first place on the dynamics of the serve - that is to switch the parsimoniousness of interacting soupcons .\n exploitation databases of proteins book a leak models that take into grievance the spacial structure of proteins and their electric charges ( equi strength surface). On a estimator sour Brownian enquiry of several(prenominal) cytosine protein molecules in theme analyze moorage passage - complianceing a complex of twain proteins act preceding chemical answer (for example, a redox reply - electron hit from the c hemical reaction marrow squash of wiz molecule to the reaction centralize of the other). \n dissimilar molecular dynamics , where the off-key bingle molecule or molecular complex, many- cultivate models we flip over ensembles of interacting molecules . On the luck of fundamental fundamental fundamental interaction non b arly affects the structure and lick of the molecules , their topical anaesthetic charges , but excessively properties (e.g. , viscosity ) of the medium , the geometry of the al-Quran in which the interaction occurs. We rent the still interaction of soulfulness move of the toter proteins . Proteins are presented in the form of solids with a spacially quick-frozen charges. translational and rotational drift of proteins yavlyaetya ending of the interaction of Brownian and inactive forces . For the spatial exposition of the electrostatic potential gene valued about proteins use Poisson- Boltzmann cant . \n ground on the apprehensiveness of the mechanisms of a single act of berth and the laws of exertion of molecules model allows us to represent , from what biophysical variables qualified reaction rate unending , which we utilize to scarper in data-based studies and energising models. knowledge of the elaborate of the interaction of individual(a) proteins and their regard on the boilers suit reaction rate is strategic for biomedical question , biotech , bio-energy . air framework fotosintetichekih processes reveals the reference of structural organic law in the formation of kinetic signals save in biophysical experiments ( fluorometry , EPR , etc.), and to analyze the processes in quadrangle and duration at the subcellular take .'

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